On May 29, 2024, the research team led by Professor Zhu Jiapeng from Nanjing University of Chinese Medicine School of Medicine and Professor Zhang Kai from Yale University published their research result, High-resolution In Situ Structures of Mammalian Respiratory Supercomplexes, online in the top international journal Nature. This study broke through the traditional concept of protein purification by directly imaging mitochondria, achieving the first high-resolution structural analysis of in-situ mitochondrial membrane proteins, obtaining the most authentic and clearest three-dimensional structure of respiratory chain supercomplexes, and providing a solid theoretical foundation for studying oxidative phosphorylation, a fundamental life process...
