The UNIQ System, a molecular network navigation system for Chinese and Western medicine based on network targets, has emerged as a new research direction represented by network pharmacology, showing rapid development trends with recent advancements in big data, artificial intelligence, and systems biology, providing new opportunities for breakthroughs in TCM research paradigms. Network pharmacology has progressed from hypothesis and concept to principles and practical applications, playing a positive role in promoting TCM inheritance and innovative development. It emerged in the context of the continuous development of systems biology and the renewed focus on "holistic" approaches in medical research, with its formation and development influenced by TCM...